ELISA-Antikörperpaar von Boster Bio
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Transthyretin (TTR) ist auch als Präalbumin bekannt. Es ist der Chromosomenregion 18q11.2-q12.1 zugeordnet. Dieses Gen kodiert ein Trägerprotein, das für den Transport von Schilddrüsenhormonen und Retinol verantwortlich ist. Das Protein besteht aus einem Tetramer identischer Untereinheiten. Aufgrund der erhöhten Stabilität der Tetramerform dieses kodierten Proteins in Mäusen im Vergleich zum menschlichen Protein hat dieses Genprodukt eine geringere Tendenz zur Bildung von Amyloidfibrillen. Beim Menschen bindet dieses Protein Beta-Amyloid, verhindert dessen Aggregation und spielt eine neuroprotektive Rolle bei der Alzheimer-Krankheit.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
TTR identifies transthyretin in Homo sapiens (Human). This target record connects NCBI Gene 7276, UniProtKB P02766 and related ABMIUM catalogue products.
