ELISA-Kit geliefert von Boster Bio
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Der Stromazell-abgeleitete Faktor 1 (SDF-1), auch bekannt als C-X-C-Motiv-Chemokin 12 (CXCL12), ist ein Chemokinprotein, das beim Menschen durch das CXCL12-Gen auf Chromosom 10 kodiert wird. Dieses antimikrobielle Gen kodiert ein Stromazell-abgeleitetes Alpha-Chemokin-Mitglied der Intercrine-Familie. Das kodierte Protein fungiert als Ligand für den G-Protein-gekoppelten Rezeptor Chemokin (C-X-C-Motiv)-Rezeptor 4 und spielt eine Rolle bei vielen verschiedenen zellulären Funktionen, einschließlich Embryogenese, Immunüberwachung, Entzündungsreaktion, Gewebehomöostase sowie Tumorwachstum und Metastasierung. Mutationen in diesem Gen sind mit der Resistenz gegen Infektionen mit dem menschlichen Immundefizienzvirus Typ 1 assoziiert. Für dieses Gen wurden mehrere Transkriptvarianten gefunden, die verschiedene Isoformen kodieren.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum und Plasma (Heparin | ||||
| EDTA) |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
C-X-C motif chemokine ligand 12 (CXCL12), widely known as stromal cell-derived factor 1 (SDF-1), is a chemokine central to chemotaxis and cell trafficking. This hub connects verified names and identifiers with ABMIUM catalogue products.
Biological function: C-X-C motif chemokine ligand 12 (CXCL12/SDF-1) is a chemoattractant for T lymphocytes and monocytes. Reviewed UniProt evidence shows signalling through CXCR4 to induce calcium responses and chemotaxis, with additional binding to the atypical chemokine receptor ACKR3.
