ELISA-Kit geliefert von Boster Bio
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Rantes (regulated on activation normal T cell expressed and secreted) ist einer der natürlichen Liganden für den Chemokinrezeptor CCR5 und unterdrückt potent die In-vitro-Replikation der R5-Stämme von HIV-1, die CCR5 als Korezeptor verwenden. Periphere Blutmononuklearzellen oder CD4 (+)-Lymphozyten, die von verschiedenen Individuen gewonnen wurden, weisen große Schwankungen in ihrer Fähigkeit auf, RANTES abzusondern. Das Rantes-Genprodukt wird auf 10 kDa geschätzt und nach Abspaltung des Signalpeptids auf etwa 8 kDa. Von den 68 Aminosäuren sind 4 Cystein, und es gibt keine Stellen für N-gebundene Glykosylierung. Rantes wird von kultivierten T-Zelllinien exprimiert, die Ag-spezifisch und wachstumsfaktorabhängig sind.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum | ||||
| Plasma (Heparin | ||||
| EDTA | ||||
| Citrat) und Urin. |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CCL5 identifies C-C motif chemokine ligand 5 in Homo sapiens (Human). This target record connects NCBI Gene 6352, UniProtKB P13501 and related ABMIUM catalogue products.
