ELISA-Kit geliefert von Boster Bio
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PTX3 (Pentraxin 3) gehört zur Superfamilie der Pentraxine. Diese Superfamilie zeichnet sich durch eine zyklische multimere Struktur aus. Das PTX3-Gen ist auf 3q25.32 kartiert. Das vorhergesagte 381 Aminosäuren umfassende PTX3-Protein weist Homologie zur Pentraxin-Proteinfamilie auf. Signifikante PTX3-Spiegel wurden im Plasma neutropenischer Patienten mit systemischer A nachgewiesen. PTX3 ist wirksam bei der Verhinderung von CMV-Infektionen und Reaktivierungen sowie nachfolgenden Aspergillus-Infektionen. PTX3 aktiviert den klassischen Komplementaktivierungsweg und erleichtert die Erkennung von Pathogenen durch Makrophagen und dendritische Zellen (DCs).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum | ||||
| Plasma (EDTA) und Speichel. |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CST3 identifies cystatin C in Homo sapiens (Human). This target record connects NCBI Gene 1471, UniProtKB P01034 and related ABMIUM catalogue products.
Biological function: CST3 (cystatin C) is an inhibitor of cysteine proteinases and acts as a local physiological regulator of cysteine-protease activity.
