ELISA-Kit geliefert von Boster Bio
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Notch-Proteine sind einfach-transmembranäre Rezeptoren, die Zellschicksalsentscheidungen während der Entwicklung regulieren. Die Notch-Familie umfasst 4 Rezeptoren, NOTCH1, NOTCH2, NOTCH3 und NOTCH4, deren Liganden JAG1, JAG2, DLL1, DLL3 und DLL4 einschließen. Notch homolog 1, Translokations-assoziiert (NOTCH1), ist ein menschliches Gen, das einen einfach-transmembranären Rezeptor kodiert. Es fungiert als Rezeptor für membrangebundene Liganden und kann während der Entwicklung mehrere Rollen spielen. NOTCH1 koordiniert möglicherweise normalerweise den Prozess der Somitogenese, und das aktivierte Notch 1 und Notch 3 fördern die Differenzierung von Vorläuferzellen zu Astroglia.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
NOTCH1 identifies notch receptor 1 in Homo sapiens (Human). This target record connects NCBI Gene 4851, UniProtKB P46531 and related ABMIUM catalogue products.
