ELISA Kit supplied by Boster Bio
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MBL2, auch bekannt als Mannose-bindendes Lektin (Protein C) 2, löslich oder Mannose-bindendes Lektin (MBL), ist ein Lektin, das eine entscheidende Rolle in der angeborenen Immunität spielt. MBL2 ist auf Chromosom 10q11.2-q21 kartiert. Es gehört zur Klasse der Kollektine in der C-Typ-Lektin-Superfamilie, deren Funktion die Mustererkennung in der ersten Verteidigungslinie des präimmunen Wirts zu sein scheint. MBL2 erkennt Kohlenhydratmuster, die auf der Oberfläche einer großen Anzahl pathogener Mikroorganismen, einschließlich Bakterien, Viren, Protozoen und Pilzen, vorkommen. Die Bindung von MBL2 an einen Mikroorganismus führt zur Aktivierung des Lektinwegs des Komplementsystems. Eine weitere wichtige Funktion von MBL2 ist, dass dieses Molekül seneszente und apoptotische Zellen bindet und die Aufnahme ganzer, intakter apoptotischer Zellen sowie von Zelltrümmern durch Phagozyten fördert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Sample Compatibility | Assay Range | Sensitivity | Specificity |
|---|---|---|---|---|
| cell culture supernatants | ||||
| cell lysates | ||||
| serum and plasma (heparin | ||||
| EDTA) |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CST3 identifies cystatin C in Homo sapiens (Human). This target record connects NCBI Gene 1471, UniProtKB P01034 and related ABMIUM catalogue products.
Biological function: CST3 (cystatin C) is an inhibitor of cysteine proteinases and acts as a local physiological regulator of cysteine-protease activity.
