ELISA-Kit geliefert von Boster Bio
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CD32 ist ein Oberflächenrezeptorprotein und Teil einer großen Population von B-Zell-Korezeptoren, die die Signalübertragung modulieren. Es hat eine geringe Affinität zu IgG-Antikörpern und reguliert die Antikörperproduktion in Anwesenheit von IgG herunter. Diese Rückkopplungsschleife reduziert im Wesentlichen die Produktion von IgG durch B-Zellen, wenn ein Überschuss im Körper vorhanden ist.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Zelllysate | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Fc gamma receptor IIb (FCGR2B), also known as CD32B, is a low-affinity IgG Fc receptor. This ABMIUM target record links the verified human identity (NCBI Gene 2213; UniProtKB P31994) to catalogue-backed research products.
Biological function: Fc gamma receptor IIb (FCGR2B/CD32B) is an inhibitory low-affinity receptor for the Fc region of IgG. It contributes to immune-complex handling and helps regulate B-cell activation and antibody production, providing an important counter-regulatory signal within Fc receptor biology.
