ELISA-Kit geliefert von Boster Bio
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Carboanhydrase 9 (CA9/CAIX) ist ein Enzym, das beim Menschen durch das CA9-Gen kodiert wird. Carboanhydrasen (CAs) sind eine große Familie von Zink-Metalloenzymen, die die reversible Hydratation von Kohlendioxid katalysieren. Sie sind an einer Vielzahl biologischer Prozesse beteiligt, einschließlich Atmung, Kalzifizierung, Säure-Basen-Gleichgewicht, Knochenresorption und der Bildung von Kammerwasser, Liquor cerebrospinalis, Speichel und Magensäure. Dieses Gen ist auf 9p13.3 kartiert. CA IX ist ein Transmembranprotein und das einzige bekannte tumorassoziierte Carboanhydrase-Isoenzym. Es wird in allen klarzelligen Nierenzellkarzinomen exprimiert, ist aber in normalen Nieren oder den meisten anderen normalen Geweben nicht nachweisbar. Es kann an der Zellproliferation und -transformation beteiligt sein.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenverträglichkeit | Testbereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum | ||||
| Plasma (Heparin | ||||
| EDTA | ||||
| Citrat) und Urin. |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Carbonic anhydrase 9 (CA9), also called carbonic anhydrase IX or CAIX, is a transmembrane zinc metalloenzyme involved in carbon dioxide/bicarbonate interconversion and pH regulation. ABMIUM catalogue products linked below support research on CA9 biology.
Biological function: Carbonic anhydrase 9 (CA9/CA IX/CAIX) is a transmembrane zinc-dependent carbonic anhydrase that catalyses the reversible interconversion of carbon dioxide and water with bicarbonate and hydrogen ions. Its expression is induced by hypoxia, linking CA9 to cellular acid-base regulation and hypoxia-associated research.
