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MAML2 Break Apart FISH-Sondenreagenz

MAML2 Break Apart FISH-Sondenreagenz von Wuhan HealthCare Biotechnology

SKU:
ABM46335
Manufacturer SKU
FP-082
Product type
FISH-Sondenreagenz
TargetMAML2/11Q21
ApplicationsFISCH
Sample typeVorbereiteter FISH-Objektträger

Manufacturer provenance

Manufactured by:
Wuhan HealthCare Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

MAML2 ist ein transkriptioneller Co-Aktivator, der in der Fusionsforschung untersucht wird, insbesondere bei Tumortypen, bei denen wiederkehrende MAML2-Rearrangements beobachtet werden.

Das Break-Apart-Design wird verwendet, um Rearrangements mit MAML2 zu untersuchen, wobei die Trennung unterschiedlich markierter Sondensignale eine Störung des Ziellokus in vorbereiteten Forschungsproben anzeigen kann.

FISH-Sonden werden auf fixierte Zellen oder präparierte Gewebeschnitte angewendet, bei denen genomische Ziele räumlich erhalten bleiben, wodurch sie für die molekulare Zytogenetik-Forschung, Tumorbiologiestudien und die Verifizierung struktureller oder numerischer Chromosomenveränderungen nützlich sind.

Dieses Produkt wird als 100µL/10 Tests RUO-Sondenreagenz von Wuhan HealthCare Biotechnology geliefert. DAPI enthalten. Es sollte versiegelt, lichtgeschützt und unter geeigneten FISH-Probenvorbereitungsbedingungen gelagert und gehandhabt werden.

Key facts & specifications
Research areas
Cytogenetics, Oncology research, Haematology research, Solid Tumors research
Also known as
MAML2 (11q21) gene break apart probe reagent, MAML2(11q21)
Available conjugations
MAML2 3' orange, MAML2 5' green, orange, green, aqua, DAPI
Incubation temperature
Hybridisierungs-Workflow abhängig vom Probenvorbereitungsprotokoll
Assay type
Fluoreszenz-in-situ-Hybridisierung (FISH)
Detection method
Fluoreszenzmikroskopie
Wells / tests
10 tests
Form / buffer
Sondenreagens
Sequence fragment
MAML2(11q21)
Quantity per pack
100 µL/10 Tests
Technical note
Probe design source text: MAML2 gene 3' end labeled as orange, with a length of 330 kb; MAML2 gene 5' end labeled as green, with a length of 800 kb. Protocol / imaging data: Hybridisation temperature: 42 °C; Hybridisation time: 2-16h; Denaturation temperature: 85°C; Denaturation time: 5min; Recommended imaging filters: DAPI + orange +green; Counterstain: DAPI; Signal interpretation: Refer to IFU; Expected normal signal pattern: Refer to IFU Label assignment: MAML2 3' orange, MAML2 5' green Cytoband(s): 11q21
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Sample type validation

Sample compatibility evidence using the same validation key.

Sample typeVorbereiteter FISH-Objektträger
Tissue
Identifiers & database references
Manufacturer SKU
FP-082
Storage, stability & shipping
Shelf life
12 Monate bei lichtgeschützter, versiegelter Lagerung bei -20°C ±5°C
Storage conditions
Dicht verschlossen und lichtgeschützt bei -20°C ±5°C lagern. Unnötiges wiederholtes Einfrieren und Auftauen vermeiden.
Shipped at
below 0 °C
Short-term storage
below 0 °C
Long-term storage
-20 °C ± 5 °C
Storage warning
Protect fluorescent probe reagent from light during handling.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Wuhan HealthCare Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Wuhan HealthCare Biotechnology
£675.00£574.00