AURKB FISH-Sondenkombination von Wuhan HealthCare Biotechnology
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AURKB ist das gelistete Sondenziel für dieses RUO-Reagenz zur Fluoreszenz-in-situ-Hybridisierung und ist je nach Ziellokus relevant für die molekulare Zytogenetik-, Onkologie- oder Hämatologieforschung.
Das gezielte FISH-Design unterstützt die Visualisierung der gelisteten genomischen Region mittels Fluoreszenzsondenhybridisierung und mikroskopiebasierter Signalbewertung.
FISH-Sonden werden auf fixierte Zellen oder präparierte Gewebeschnitte angewendet, bei denen genomische Ziele räumlich erhalten bleiben, wodurch sie für die molekulare Zytogenetikforschung, Tumorforschungsstudien und die Verifizierung struktureller oder numerischer Chromosomenveränderungen nützlich sind.
Dieses Produkt wird als 100µL/10 Tests RUO-Sondenreagenz von Wuhan HealthCare Biotechnology geliefert. DAPI ist enthalten. Es sollte versiegelt, lichtgeschützt und unter Anwendung geeigneter FISH-Probenvorbereitungsbedingungen gelagert werden.
Fully tested in-house by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Präparierter FISH-Objektträger |
|---|---|
| Prepared FISH slide |
This product is manufactured by Wuhan HealthCare Biotechnology and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AURKB encodes Aurora kinase B, a serine/threonine kinase component of the chromosomal passenger complex and a major regulator of mitosis and cytokinesis. This target record connects reviewed human AURKB identifiers with ABMIUM catalogue products targeting Aurora B/AURKB.
Biological function: AURKB is a serine/threonine kinase within the chromosomal passenger complex. It regulates chromosome alignment and segregation, kinetochore-microtubule attachment, spindle organisation and the onset and completion of cytokinesis. AURKB phosphorylates chromosomal-passenger-complex components and multiple mitotic substrates, and participates in the abscission checkpoint that prevents premature cytokinetic separation when chromosome bridges persist.
