GMDS Kaninchen-pAk von ELK Biotechnology
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GMDS-Kaninchen-pAk ist ein Antikörper von ELK Biotechnology für Forschungsabläufe, die GMDS betreffen.
Die GDP-Mannose-4,6-Dehydratase (GMD; EC 4.2.1.47) katalysiert die Umwandlung von GDP-Mannose zu GDP-4-Keto-6-Desoxymannose, dem ersten Schritt in der Synthese von GDP-Fucose aus GDP-Mannose, unter Verwendung von NADP+ als Kofaktor. Die zweiten und dritten Schritte des Signalwegs werden durch ein einziges Enzym, die GDP-Keto-6-Desoxymannose-3,5-Epimerase, 4-Reduktase, im Menschen als FX bezeichnet (MIM 137020), katalysiert [bereitgestellt von OMIM, Aug. 2009].
| Spezifität | GMDS-polyklonaler Antikörper weist endogene Proteinkonzentrationen nach. |
|---|---|
| Validierungsnachweislegenden | Western-Blot-Analyse von Lysaten aus SH-SY5Y-Zellen, Primärantikörper wurde 1:1000 verdünnt, 4° über Nacht |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.