ADA-Kaninchen-pAb von ELK Biotechnology
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ADA Kaninchen-pAk ist ein Antikörper von ELK Biotechnology für Forschungsabläufe, die ADA betreffen.
Dieses Gen kodiert ein Enzym, das die Hydrolyse von Adenosin zu Inosin katalysiert. Für dieses Gen wurden verschiedene Mutationen beschrieben, die mit menschlichen Krankheiten in Verbindung gebracht werden. Ein Mangel an diesem Enzym verursacht eine Form der schweren kombinierten Immundefizienz (SCID), bei der eine Dysfunktion der B- und T-Lymphozyten mit eingeschränkter zellulärer Immunität und verminderter Produktion von Immunglobulinen vorliegt, während erhöhte Spiegel dieses Enzyms mit angeborener hämolytischer Anämie in Verbindung gebracht wurden. [bereitgestellt von RefSeq, Juli 2008].
| Spezifität | ADA Polyclonal Antibody weist endogene Proteinspiegel nach. |
|---|---|
| Beschriftungen der Validierungsnachweise | Western-Blot-Analyse von Lysaten aus K562-Zellen, Primärantikörper wurde 1:1000 verdünnt, 4° über Nacht |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Ratte | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Adenosine deaminase (ADA), also known as ADA1, is an enzyme of purine metabolism that deaminates adenosine and 2-deoxyadenosine. This ABMIUM target record links ADA biology, verified human identifiers and catalogue-backed research products.
Biological function: ADA catalyzes hydrolytic deamination of adenosine to inosine and 2-deoxyadenosine to deoxyinosine, helping regulate purine metabolism and adenosine homeostasis. Reviewed UniProt annotation also describes extracellular signalling roles associated with cell-surface ADA.
