TRPV4-Kaninchen-pAk von ELK Biotechnology
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TRPV4-Kaninchen-pAb ist ein ELK Biotechnology-Antikörper für Forschungsabläufe, die TRPV4 betreffen.
transient receptor potential cation channel subfamily V member 4 (TRPV4) Homo sapiens Dieses Gen kodiert ein Mitglied der OSM9-ähnlichen Transient-Rezeptor-Potential-Kanal-(OTRPC)-Unterfamilie in der Transient-Rezeptor-Potential-(TRP)-Superfamilie von Ionenkanälen. Das kodierte Protein ist ein Ca2+-permeabler, nicht-selektiver Kationenkanal, der vermutlich an der Regulierung des systemischen osmotischen Drucks beteiligt ist. Mutationen in diesem Gen sind die Ursache für spondylometaphysäre und metatropische Dysplasie sowie die hereditäre motorische und sensible Neuropathie Typ IIC. Für dieses Gen wurden mehrere Transkriptvarianten gefunden, die verschiedene Isoformen kodieren. [bereitgestellt von RefSeq, Apr 2010]
| Spezifität | TRPV4-polyklonaler Antikörper detektiert endogene Spiegel des TRPV4-Proteins. |
|---|---|
| Validierungsnachweislegenden | Western-Blot-Analyse von Extrakten aus K562-Zellen unter Verwendung von TRPV4-polyklonalem Antikörper. Sekundärantikörper (Katalognummer: RS0002) wurde 1:20000 verdünnt | Western-Blot-Analyse von Lysaten aus PC12-Zellen unter Verwendung von TRPV4-Antikörper. |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
TRPV4 identifies transient receptor potential cation channel subfamily V member 4 in Homo sapiens (Human). This target record connects NCBI Gene 59341, UniProtKB Q9HBA0 and related ABMIUM catalogue products.
