ATG3 Kaninchen-pAk von ELK Biotechnology
Know who made it. See the evidence. Buy through one marketplace.
ATG3 Kaninchen-pAk ist ein ELK Biotechnology-Antikörper für Forschungsabläufe mit ATG3.
Dieses Gen kodiert ein Ubiquitin-ähnliches-konjugierendes Enzym und ist ein Bestandteil von Ubiquitinierungs-ähnlichen Systemen, die an der Autophagie beteiligt sind, dem Prozess des Abbaus, Umsatzes und Recyclings zytoplasmatischer Bestandteile in eukaryotischen Zellen. Dieses Protein spielt bekanntermaßen eine Rolle bei der Regulierung der Autophagie während des Zelltods. Ein Pseudogen dieses Gens befindet sich auf Chromosom 20. Alternatives Spleißen führt zu mehreren Transkriptvarianten, die verschiedene Isoformen kodieren. [bereitgestellt von RefSeq, Juli 2013],
| Spezifität | Dieser Antikörper detektiert endogene ATG3-Spiegel in Human/Maus/Ratte |
|---|---|
| Validierungsnachweis-Beschriftungen | Western-Blot-Analyse von Lysaten aus HEK293-Zellen, primärer Antikörper wurde 1:1000 verdünnt, 4° über Nacht |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ATG3 encodes an E2-like conjugating enzyme required for lipidation of ATG8-family proteins during autophagosome formation. This target record connects reviewed human ATG3 identifiers with ABMIUM catalogue products targeting ATG3.
Biological function: ATG3 is an E2 conjugating enzyme in the autophagy machinery. It catalyses covalent conjugation of ATG8-family proteins, including LC3 and GABARAP family members, to phosphatidylethanolamine-containing membrane lipids. ATG3 cycles between ATG7-mediated loading and the ATG12-ATG5-ATG16L1 E3-like complex to promote ATG8 lipidation and formation of autophagic isolation membranes.
