GDF11-Kaninchen-pAk von ELK Biotechnology
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GDF11 Kaninchen-pAk ist ein ELK Biotechnology Antikörper für Forschungsabläufe, die GDF11 betreffen.
Dieses Gen kodiert einen sezernierten Liganden der TGF-beta (Transformierender Wachstumsfaktor-beta)-Superfamilie von Proteinen. Liganden dieser Familie binden verschiedene TGF-beta-Rezeptoren, was zur Rekrutierung und Aktivierung von SMAD-Familien-Transkriptionsfaktoren führt, die die Genexpression regulieren. Das kodierte Präproprotein wird proteolytisch prozessiert, um jede Untereinheit des disulfidverbrückten Homodimers zu erzeugen. Dieses Protein spielt eine Rolle bei der Entwicklung des Nerven- und anderer Organsysteme und kann das Altern regulieren. [bereitgestellt von RefSeq, Aug 2016].
| Spezifität | Dieser Antikörper detektiert endogene GDF11-Spiegel bei Mensch/Maus/Ratte |
|---|---|
| Nachweis der Validierung | Western-Blot-Analyse von Lysaten aus A549-Zellen, Primärantikörper wurde 1:1000 verdünnt, 4° über Nacht |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
GDF11 identifies growth differentiation factor 11 in Homo sapiens (Human). This target record connects NCBI Gene 10220, UniProtKB O95390 and related ABMIUM catalogue products.
