ADAMTS-1 Kaninchen-pAk von ELK Biotechnology
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ADAMTS-1 Kaninchen-pAk ist ein ELK Biotechnology-Antikörper für Forschungsabläufe mit ADAMTS-1.
Dieses Gen kodiert ein Mitglied der ADAMTS-Proteinfamilie (A Disintegrin And Metalloproteinase with Thrombospondin Motif). Mitglieder dieser Familie teilen mehrere unterschiedliche Proteinmodule, darunter eine Propeptidregion, eine Metalloproteinasedomäne, eine Disintegrin-ähnliche Domäne und ein Thrombospondin-Typ-1 (TS)-Motiv. Einzelne Mitglieder dieser Familie unterscheiden sich in der Anzahl der C-terminalen TS-Motive, und einige weisen einzigartige C-terminale Domänen auf. Das durch dieses Gen kodierte Protein enthält zwei Disintegrin-Loops und drei C-terminale TS-Motive und besitzt antiangiogene Aktivität. Die Expression dieses Gens kann mit verschiedenen entzündlichen Prozessen sowie der Entwicklung von Krebskachexie assoziiert sein. Dieses Gen ist wahrscheinlich für normales Wachstum, Fruchtbarkeit sowie Organmorphologie und -funktion notwendig. [bereitgestellt von RefSeq, Juli 2008].
| Spezifität | ADAMTS-1 Polyclonal Antibody detektiert endogene Mengen an ADAMTS-1 Protein. |
|---|---|
| Nachweisbilder Validierung | Western Blot Analyse verschiedener Zellen mit ADAMTS-1 Polyclonal Antibody | Western Blot Analyse von HUVEC-Zellen mit ADAMTS-1 Polyclonal Antibody |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Ratte | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ADAM metallopeptidase with thrombospondin type 1 motif 1 (ADAMTS1/ADAMTS-1), also known as METH-1, is a secreted extracellular metalloprotease. This ABMIUM guide connects its verified identity to catalogue-backed research products and authoritative NCBI/UniProt evidence.
Biological function: ADAMTS1 is a secreted metalloprotease of the ADAMTS family. Reviewed UniProt reports cleavage of extracellular-matrix substrates including aggrecan and cartilage oligomeric matrix protein (COMP), together with anti-angiogenic activity and a proposed role in follicular rupture.
