TPP1 Kaninchen pAk von ELK Biotechnology
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TPP1-Kaninchen-pAk ist ein Antikörper von ELK Biotechnology für Forschungsabläufe, die TPP1 betreffen.
Dieses Gen kodiert ein Mitglied der Sedolisin-Familie von Serinproteasen. Die Protease funktioniert im Lysosom, um N-terminale Tripeptide von Substraten abzuspalten, und hat eine schwächere Endopeptidaseaktivität. Sie wird als katalytisch inaktives Enzym synthetisiert, das bei Ansäuerung aktiviert und autoproteolysiert wird. Mutationen in diesem Gen führen zu einer spätinfantilen neuronalen Ceroidlipofuszinose, die mit dem Versagen des Abbaus spezifischer Neuropeptide und einer Untereinheit der ATP-Synthase im Lysosom verbunden ist. [bereitgestellt von RefSeq, Juli 2008],
| Spezifität | TPP1 polyklonaler Antikörper detektiert endogene Proteinspiegel. |
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Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Ratte | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.