TREM2 Kaninchen-pAk von ELK Biotechnology
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TREM2 Kaninchen-pAk ist ein Antikörper von ELK Biotechnology für Forschungsabläufe, die TREM2 betreffen.
Triggering Receptor expressed on myeloid cells 2 (TREM2) Homo sapiens Dieses Gen kodiert für ein Membranprotein, das einen Rezeptorsignalkomplex mit dem TYRO-Proteintyrosinkinase-bindenden Protein bildet. Das kodierte Protein fungiert in der Immunantwort und kann durch die Auslösung der Produktion konstitutiver entzündlicher Zytokine an chronischen Entzündungen beteiligt sein. Defekte in diesem Gen sind eine Ursache für die polyzystische lipomembranöse Osteodysplasie mit sklerosierender Leukoenzephalopathie (PLOSL). Alternatives Spleißen führt zu mehreren Transkriptvarianten, die verschiedene Isoformen kodieren. [bereitgestellt von RefSeq, Nov 2012]
| Spezifität | TREM2 Polyclonal Antibody detektiert endogene Proteinspiegel. |
|---|---|
| Validierungsnachweisbeschriftungen | Western-Blot-Analyse von Lysaten aus DU145-Zellen, Primärantikörper wurde 1:1000 verdünnt, 4° über Nacht |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
TREM2 identifies triggering receptor expressed on myeloid cells 2 in Homo sapiens (Human). This target record connects NCBI Gene 54209, UniProtKB Q9NZC2 and related ABMIUM catalogue products.
