Lamin B1 Maus-mAb von ELK Biotechnology
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Lamin B1 Mouse mAb ist ein Antikörper von ELK Biotechnology für Forschungsabläufe, die Lamin B1 betreffen.
Die Kernlamina besteht aus einer zweidimensionalen Matrix von Proteinen, die sich neben der inneren Kernmembran befindet. Die Lamin-Proteinfamilie bildet die Matrix und ist in der Evolution hochkonserviert. Während der Mitose wird die Lamina-Matrix reversibel abgebaut, da die Lamin-Proteine phosphoryliert werden. Lamin-Proteine sollen an der nukleären Stabilität, der Chromatin-Struktur und der Genexpression beteiligt sein. Wirbeltier-Lamine bestehen aus zwei Typen, A und B. Dieses Gen kodiert eines der beiden B-Typ-Proteine, B1.
| Validierungsnachweise | Western-Blot-Analyse von 1) HepG2, 2) 293T, 3) Maus-Hirngewebe, 4) Ratten-Hirngewebe mit EM1035, verdünnt auf 1:5.000. | 1、Input: Maus-Hirngewebe-Lysat 2、IP-Produkt: IP verdünnt 1:200 Western-Blot-Analyse: Primärantikörper: EM1035 1:5.000 Sekundärantikörper: Ziegen-anti-Maus-IgG, leichtkettenspezifisch (S003), 1:5.000 |
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Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Ratte | |||||||
| Maus |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
LMNB1 identifies lamin B1 in Homo sapiens (Human). This target record connects NCBI Gene 4001, UniProtKB P20700 and related ABMIUM catalogue products.
