Primärer Antikörper geliefert von Boster Bio
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Das embryonale Drosophila-Protein SNAI1, gemeinhin bekannt als Snail, ist ein Zinkfinger-Transkriptionsrepression, der die Expression ektodermaler Gene innerhalb des Mesoderms herunterreguliert. Es befindet sich in 16q24.3. Das nukleäre Protein, das von diesem Gen kodiert wird, ist strukturell dem Drosophila-Snail-Protein ähnlich und wird ebenfalls als entscheidend für die Mesodermbildung im sich entwickelnden Embryo angesehen. Mindestens zwei Varianten eines ähnlichen prozessierten Pseudogens wurden auf Chromosom 2 gefunden. Es wird angenommen, dass das SNAIL-Gen eine Rolle bei der Rezidivrate von Brustkrebs spielen könnte, indem es E-Cadherin herunterreguliert und einen epithelial-mesenchymalen Übergang induziert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | FACS | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
