Primärantikörper geliefert von Boster Bio
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NAD-abhängige Deacetylase Sirtuin-3, mitochondrial, auch bekannt als SIRT3, ist ein Protein, das beim Menschen durch das SIRT3-Gen kodiert wird. SIRT3 kodiert für ein Mitglied der Sirtuin-Familie der Histondeacetylasen der Klasse III, Homologe des Hefe-Sir2-Proteins. Das kodierte Protein findet sich ausschließlich in Mitochondrien, wo es reaktive Sauerstoffspezies eliminieren, Apoptose hemmen und die Bildung von Krebszellen verhindern kann. SIRT3 hat weitreichende Auswirkungen auf die nukleäre Genexpression, Krebs, Herz-Kreislauf-Erkrankungen, Neuroprotektion, Alterung und Stoffwechselkontrolle.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
SIRT3 identifies sirtuin 3 in Homo sapiens (Human). This target record connects NCBI Gene 23410, UniProtKB Q9NTG7 and related ABMIUM catalogue products.
