Primärantikörper geliefert von Boster Bio
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Serin/Threonin-Proteinkinase Sgk1, auch bekannt als Serum- und Glucocorticoid-regulierte Kinase 1, ist ein Enzym, das beim Menschen durch das SGK1-Gen kodiert wird. Es ist auf 6q23.2 kartiert. Dieses Gen kodiert eine Serin/Threonin-Proteinkinase, die eine wichtige Rolle bei der zellulären Stressantwort spielt. Diese Kinase aktiviert bestimmte Kalium-, Natrium- und Chloridkanäle, was auf eine Beteiligung an der Regulation von Prozessen wie Zellüberleben, neuronaler Erregbarkeit und renaler Natriumausscheidung hindeutet. Hohe Expressionsniveaus dieses Gens können zu Erkrankungen wie Hypertonie und diabetischer Nephropathie beitragen. Für dieses Gen wurden mehrere alternativ gespleißte Transkriptvarianten, die verschiedene Isoformen kodieren, festgestellt.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
SGK1 identifies serum/glucocorticoid regulated kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 6446, UniProtKB O00141 and related ABMIUM catalogue products.
