Primärantikörper geliefert von Boster Bio
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Sin3A-assoziiertes Protein, 30kDa, auch bekannt als SAP30, ist ein Protein, das beim Menschen durch das SAP30-Gen kodiert wird. Die Histonacetylierung spielt eine Schlüsselrolle bei der Regulation der eukaryotischen Genexpression. Histonacetylierung und -deacetylierung werden durch Multisubunit-Komplexe katalysiert. Das durch dieses Gen kodierte Protein ist eine Komponente des Histondeacetylase-Komplexes, der SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48 und andere Polypeptide umfasst. Dieser Komplex ist aktiv bei der Deacetylierung von Kernhistonoktameren, aber inaktiv bei der Deacetylierung von nukleosomalen Histonen. Ein Pseudogen dieses Gens befindet sich auf Chromosom 3.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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