Primärantikörper geliefert von Boster Bio
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Das S100-Kalzium-bindende Protein A6 (S100A6) ist ein Protein, das beim Menschen vom S100A6-Gen kodiert wird. Das von diesem Gen kodierte Protein gehört zur S100-Proteinfamilie, die 2 EF-Hand-Kalziumbindungs-Motive enthält. S100-Proteine sind im Zytoplasma und/oder Zellkern einer Vielzahl von Zellen lokalisiert und an der Regulation einer Reihe zellulärer Prozesse wie Zellzyklusprogression und Differenzierung beteiligt. Die S100-Gene umfassen mindestens 13 Mitglieder, die als Cluster auf Chromosom 1q21 liegen. Dieses Protein kann an der Stimulation der Ca2+-abhängigen Insulinfreisetzung, der Stimulation der Prolaktinsekretion und der Exozytose beteiligt sein. Chromosomale Umlagerungen und eine veränderte Expression dieses Gens wurden bei Melanomen nachgewiesen.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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S100A6 identifies S100 calcium binding protein A6 in Homo sapiens (Human). This target record connects NCBI Gene 6277, UniProtKB P06703 and related ABMIUM catalogue products.
