Primärantikörper geliefert von Boster Bio
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Die doppelsträngige RNA-spezifische Editase 1 ist ein Enzym, das beim Menschen durch das ADARB1-Gen kodiert wird. Dieses Gen kodiert das Enzym, das für die prä-mRNA-Editierung der Glutamatrezeptor-Untereinheit B durch ortsspezifische Desaminierung von Adenosinen verantwortlich ist. Studien an Ratten fanden heraus, dass dieses Enzym auf seine eigenen prä-mRNA-Moleküle einwirkte, um ein AA-Dinukleotid in ein AI-Dinukleotid umzuwandeln, was zu einer neuen Spleißstelle führte. Alternatives Spleißen dieses Gens führt zu mehreren Transkriptvarianten, von denen einige durch das Vorhandensein oder Fehlen eines ALU-Kassetteninserts und einer kurzen oder langen C-terminalen Region charakterisiert wurden.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
