Primärantikörper geliefert von Boster Bio
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Liprin-alpha-1 ist ein Protein, das beim Menschen durch das PPFIA1-Gen kodiert wird. Das durch dieses Gen kodierte Protein gehört zur LAR-Protein-Tyrosin-Phosphatase-interagierenden Protein (Liprin)-Familie. Liprine interagieren mit Mitgliedern der LAR-Familie von Transmembran-Protein-Tyrosin-Phosphatasen, die bekanntermaßen wichtig für die Axonführung und die Entwicklung der Brustdrüse sind. Dieses Protein bindet an die intrazelluläre membrandistale Phosphatasedomäne der Tyrosinphosphatase LAR und scheint LAR an Zellfokaladhäsionen zu lokalisieren. Diese Interaktion könnte die Demontage von Fokaladhäsionen regulieren und somit dazu beitragen, Zell-Matrix-Interaktionen zu orchestrieren. Alternativ gespleißte Transkriptvarianten, die unterschiedliche Isoformen kodieren, wurden beschrieben.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.