Primärantikörper von Boster Bio
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Serum-Paraoxonase/Arylesterase 1 (PON1), auch bekannt als aromatische Esterase 1, ist ein Enzym, das beim Menschen durch das PON1-Gen kodiert wird. Es ist auf 7q21.3 kartiert. Dieses Gen hat eine Esterase- und insbesondere eine Paraoxonase-Aktivität. PON1 ist für die Hydrolyse von Organophosphat-Pestiziden und Nervengasen verantwortlich. Polymorphismen im PON1-Gen beeinflussen die katalytische Fähigkeit des Enzyms erheblich. PON1 (Paraoxonase 1) ist auch ein wichtiger anti-atherosklerotischer Bestandteil von High-Density-Lipoprotein (HDL). Das PON1-Gen wird durch PPAR-γ aktiviert, das die Synthese und Freisetzung von Paraoxonase 1-Enzym aus der Leber erhöht und so die Atherosklerose reduziert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Mouse |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
PON1 identifies paraoxonase 1 in Homo sapiens (Human). This target record connects NCBI Gene 5444, UniProtKB P27169 and related ABMIUM catalogue products.
