Primärantikörper geliefert von Boster Bio
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Der N-Methyl-D-Aspartat-Rezeptor 2B, auch als GRIN2B bezeichnet. Die Sequenz des vorhergesagten 1.484 Aminosäuren umfassenden menschlichen Proteins ist zu 98 % und 96 % identisch mit den Sequenzen der Nmdar2b-Proteine von Ratte bzw. Maus. Das Nmdar2B-Gen befindet sich auf dem Maus-Chromosom 6 zwischen Rho und Ly49 zentromerisch und Glb telomerisch. Die Kartierung des menschlichen NMDAR2B-Rezeptor-Untereinheit-Gens (GRIN2B) auf Chromosom 12p12, Überexpression des NMDA-Rezeptors 2B (NR2B) in den Vorderhirnen transgener Mäuse führt zu einer verstärkten Aktivierung von NMDA-Rezeptoren, was die synaptische Potenzierung als Reaktion auf Stimulationen bei 10-100 Hz erleichtert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
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GRIN2B identifies glutamate ionotropic receptor NMDA type subunit 2B in Homo sapiens (Human). This target record connects NCBI Gene 2904, UniProtKB Q13224 and related ABMIUM catalogue products.
