Primärantikörper geliefert von Boster Bio
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Der nukleäre Rezeptor-Koaktivator 4 ist ein Protein, das beim Menschen durch das NCOA4-Gen kodiert wird. Dieses Gen kodiert einen Androgenrezeptor-Koaktivator. Das kodierte Protein interagiert mit dem Androgenrezeptor in einer Liganden-abhängigen Weise, um dessen Transkriptionsaktivität zu verstärken. Chromosomentranslokationen zwischen diesem Gen und dem Ret-Tyrosinkinase-Gen, das sich ebenfalls auf Chromosom 10 befindet, wurden mit dem papillären Schilddrüsenkarzinom in Verbindung gebracht. Es wurden alternativ gespleißte Transkriptvarianten beschrieben. Pseudogene sind auf den Chromosomen 4, 5, 10 und 14 vorhanden.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.