Primärantikörper geliefert von Boster Bio
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Serin/Threonin-Proteinkinase TBK1, auch TANK-bindende Kinase 1 oder NF-kappa-B-aktivierende Kinase genannt, ist ein Enzym, das beim Menschen durch das TBK1-Gen kodiert wird. Das Gen wurde auf den menschlichen Chromosom 12q14.2 zugeordnet. Die Serin/Threonin-Kinase spielt eine wesentliche Rolle bei der Regulierung von Entzündungsreaktionen auf Fremdstoffe. TBK1 und die NF-kappa-B-Signalgebung sind essentiell in KRAS-mutierten Tumoren und etablierten einen allgemeinen Ansatz zur rationalen Identifizierung von kodependenten Signalwegen bei Krebs.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
TBK1 identifies TANK binding kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 29110, UniProtKB Q9UHD2 and related ABMIUM catalogue products.
