Primärantikörper geliefert von Boster Bio
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Interleukin-17A ist ein Protein, das beim Menschen durch das IL17A-Gen kodiert wird. Das durch dieses Gen kodierte Protein ist ein proinflammatorisches Zytokin, das von aktivierten T-Zellen produziert wird. Dieses Zytokin reguliert die Aktivitäten von NF-kappaB und Mitogen-aktivierten Proteinkinasen. Dieses Zytokin kann die Expression von IL6 und Cyclooxygenase-2 (PTGS2/COX-2) stimulieren sowie die Produktion von Stickoxid (NO) verstärken. Hohe Spiegel dieses Zytokins sind mit mehreren chronisch-entzündlichen Erkrankungen wie rheumatoider Arthritis, Psoriasis und Multipler Sklerose assoziiert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Mouse |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL17A identifies interleukin 17A in Homo sapiens (Human). This target record connects NCBI Gene 3605, UniProtKB Q16552 and related ABMIUM catalogue products.
Biological function: IL17A is a pro-inflammatory cytokine that promotes inflammatory mediator production and antimicrobial host-defence responses in multiple responsive cell types, particularly at barrier tissues.
