Primärantikörper geliefert von Boster Bio
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CD54, auch bekannt als ICAM-1. Interzelluläres Adhäsionsmolekül-1 (ICAM1) ist ein Ligand für Lymphozyten-Funktions-assoziierte (LFA) Antigene. ICAM-1 ist ein integrales Membranprotein, ein Mitglied der Immunglobulin-Superfamilie und ein Ligand für LFA-1, ein Beta-2-Leukozytenintegrin. Dieses Protein ist der wichtigste menschliche Rhinovirus-Rezeptor. Das ICAM1-Gen ist auf dem menschlichen Chromosom 19 kartiert. Beim Menschen wird die Lymphozytenadhäsion an Zellen durch das Protein-Heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) und seinen Liganden CD54 (ICAM-1) vermittelt.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ICAM1 identifies intercellular adhesion molecule 1 in Homo sapiens (Human). This target record connects NCBI Gene 3383, UniProtKB P05362 and related ABMIUM catalogue products.
Biological function: ICAM1 is a cell-adhesion molecule that supports leukocyte cell-cell adhesion and trans-endothelial migration. It serves as a ligand for leukocyte integrin receptors including LFA-1 and MAC-1, helping coordinate immune-cell adhesion and trafficking.
