Primärantikörper geliefert von Boster Bio
Know who made it. See the evidence. Buy through one marketplace.
Die Hitzeschockproteine (HSP) gehören zu einer größeren Gruppe von Polypeptiden, den Stressproteinen, die in verschiedenen Kombinationen als Reaktion auf Umweltbelastungen und Entwicklungsübergänge induziert werden. Hitzeschock 27-kD-Protein1, auch bekannt als HSPB. Die Synthese des kleinen (27-kD) HSP korreliert mit dem Erwerb von Thermotoleranz. Das HSP27-Gen ist auf 7q11.23 kartiert. Mutiertes kleines Hitzeschockprotein 27 verursacht axonale Charcot-Marie-Tooth-Krankheit und distale hereditäre motorische Neuropathie. Hitzeschockprotein 27 verhindert zelluläre Polyglutamin-Toxizität und unterdrückt die Zunahme reaktiver Sauerstoffspezies, die durch Huntingtin verursacht werden.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rabbit | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Heat shock protein family B (small) member 1 (HSPB1), widely known as HSP27, is a small heat-shock molecular chaperone. This ABMIUM record links human HSPB1 (NCBI Gene 3315; UniProt P04792) to catalogue-backed research products.
Biological function: HSPB1/HSP27 is a small heat-shock protein that responds to cellular stress and functions as a molecular chaperone supporting correct protein folding. It also contributes to differentiation and cellular stress responses.
