Primärantikörper geliefert von Boster Bio
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Holliday Junction Recognition Protein ist ein Protein im Menschen, das durch das HJURP-Gen kodiert wird. HJURP (Holliday Junction Recognition Protein) ist ein Proteinkodierungsgen. Zu den mit HJURP assoziierten Krankheiten gehört das fibrilläre Astrozytom. Zu den verwandten Signalwegen gehören DNA-Schäden und Chromosomenwartung. Zentromerisches Protein, das eine zentrale Rolle bei der Integration und Aufrechterhaltung der Histon H3-ähnlichen Variante CENPA an den Zentromeren spielt. Wirkt als spezifisches Chaperon für CENPA und ist für die Integration neu synthetisierter CENPA-Moleküle in Nukleosomen an replizierten Zentromeren erforderlich. Verhindert die CENPA-H4-Tetramerisierung und verhindert die vorzeitige DNA-Bindung durch das CENPA-H4-Tetramer. Bindet Holliday-Junctions.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.