Primärantikörper geliefert von Boster Bio
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Das kodierte Protein katalysiert die Decarboxylierung von L-3,4-Dihydroxyphenylalanin (DOPA) zu Dopamin, L-5-Hydroxytryptophan zu Serotonin und L-Tryptophan zu Tryptamin. Defekte in diesem Gen sind die Ursache für den Mangel an aromatischer L-Aminosäure-Decarboxylase (AADCD). Der AADCD-Mangel ist ein angeborener Fehler im Neurotransmitterstoffwechsel, der zu einem kombinierten Serotonin- und Katecholaminmangel führt. Für dieses Gen wurden mehrere alternativ gespleißte Transkriptvarianten identifiziert, die verschiedene Isoformen kodieren.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
DDC identifies dopa decarboxylase in Homo sapiens (Human). This target record connects NCBI Gene 1644, UniProtKB P20711 and related ABMIUM catalogue products.
