Primärantikörper geliefert von Boster Bio
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CXCR2 ist ein Rezeptor für Interleukin 8, einen starken chemotaktischen Faktor für Neutrophile. Er gehört zur GPCR-Familie (Unterfamilie Chemokine). Die Bindung von IL8 an den Rezeptor führt zur Aktivierung von Neutrophilen. Diese Reaktion wird über ein G-Protein vermittelt, das ein Phosphatidylinositol-Kalzium-Second-Messenger-System aktiviert. Dieser Rezeptor bindet mit hoher Affinität an IL8 sowie an GRO/MGSA und NAP2. Es wurde berichtet, dass er in einer Vielzahl von Geweben exprimiert wird. ESTs wurden aus menschlichen Plazenta- und Thymusbibliotheken isoliert.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Mensch | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CXCR2 identifies C-X-C motif chemokine receptor 2 in Homo sapiens (Human). This target record connects NCBI Gene 3579, UniProtKB P25025 and related ABMIUM catalogue products.
