Primärantikörper geliefert von Boster Bio
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Dieses Gen kodiert ein Serumglykoprotein, das zusammen mit den Komplementkomponenten C5b, C6, C8 und C9 einen Membranangriffskomplex als Teil des terminalen Komplementwegs des angeborenen Immunsystems bildet. Das vom Gen kodierte Protein enthält eine Cholesterin-abhängige Cytolysin/Membranangriffskomplex/Perforin-ähnliche (CDC/MACPF) Domäne und gehört zu einer großen Familie strukturell verwandter Moleküle, die Poren bilden, die an der Wirtsimmunität und der bakteriellen Pathogenese beteiligt sind. Dieses Protein initiiert die Bildung des Membranangriffskomplexes, indem es die C5b-C6-Unterkomplex bindet und sich in die Phospholipiddoppelschicht einfügt, wodurch es als Membrananker dient. Mutationen in diesem Gen sind mit einer seltenen Erkrankung namens C7-Mangel verbunden.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CXCL10 identifies C-X-C motif chemokine ligand 10 in Homo sapiens (Human). This target record connects NCBI Gene 3627, UniProtKB P02778 and related ABMIUM catalogue products.
