Primärantikörper geliefert von Boster Bio
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Nervenwachstumsfaktor ist ein Polypeptid, das an der Regulierung des Wachstums und der Differenzierung sympathischer und bestimmter sensorischer Neuronen beteiligt ist. Die Nukleotidsequenz von menschlichem und Maus-Beta-NGF ist sehr ähnlich. Die Beta-Untereinheiten des Nervenwachstumsfaktors (NGFB) wurden dem Maus-Chromosom 3 und dem menschlichen Chromosom 1p22 zugeordnet. Das menschliche Gen für die Beta-Untereinheit des Nervenwachstumsfaktors befindet sich auf dem proximalen kurzen Arm des Chromosoms 1. Eine Mutation im Nervenwachstumsfaktor-Beta-Gen (NGFB) führt zum Verlust der Schmerzwahrnehmung.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
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NGF identifies nerve growth factor in Homo sapiens (Human). This target record connects NCBI Gene 4803, UniProtKB P01138 and related ABMIUM catalogue products.
Biological function: NGF is a neurotrophin required for development and maintenance of sympathetic and sensory neurons. Mature NGF signals through NTRK1 and NGFR to regulate neuronal survival, differentiation and growth.
