Primärantikörper geliefert von Boster Bio
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Das Chemokin (C-X-C-Motiv) Ligand 13 (CXCL13), auch bekannt als B-Lymphozyten-Chemoattraktans (BLC) oder B-Zellen-anziehendes Chemokin 1 (BCA-1), ist ein Proteinligand, der beim Menschen durch das CXCL13-Gen kodiert wird. Das B-Lymphozyten-Chemoattraktans, unabhängig kloniert und Angie genannt, ist ein antimikrobielles Peptid und CXC-Chemokin, das stark in den Follikeln der Milz, der Lymphknoten und der Peyer-Plaques exprimiert wird. Es fördert bevorzugt die Migration von B-Lymphozyten (im Vergleich zu T-Zellen und Makrophagen), offenbar durch die Stimulierung des Kalziumeinstroms in und der Chemotaxis von Zellen, die den Burkitt-Lymphom-Rezeptor 1 (BLR-1) exprimieren. Es könnte daher bei der Wanderung von B-Lymphozyten in die Follikel eine Rolle spielen.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CXCL13 identifies C-X-C motif chemokine ligand 13 in Homo sapiens (Human). This target record connects NCBI Gene 10563, UniProtKB O43927 and related ABMIUM catalogue products.
