Primärantikörper geliefert von Boster Bio
Know who made it. See the evidence. Buy through one marketplace.
Der Arylhydrocarbon-Rezeptor (AhR oder AHR oder ahr oder ahR) ist ein Protein, das beim Menschen vom AHR-Gen kodiert wird. Es ist auf 7p21.1 kartiert. Das von diesem Gen kodierte Protein ist ein Liganden-aktivierter Helix-Loop-Helix-Transkriptionsfaktor, der an der Regulierung biologischer Reaktionen auf planare aromatische Kohlenwasserstoffe beteiligt ist. Dieser Rezeptor reguliert Xenobiotika-metabolisierende Enzyme wie Cytochrom P450. Vor der Ligandenbindung wird das kodierte Protein im Zytoplasma sequestriert; nach der Ligandenbindung wandert dieses Protein in den Zellkern und stimuliert die Transkription von Zielgenen.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Maus | ||||||||
| Ratte |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AHR is the aryl hydrocarbon receptor, also known as AhR or Ah receptor. This ligand-activated transcription factor senses diverse environmental, dietary, microbial and endogenous compounds and converts ligand binding into regulated gene-expression programmes.
Biological function: AHR is a ligand-activated basic helix-loop-helix transcription factor. After ligand binding it translocates to the nucleus, heterodimerizes with ARNT and binds xenobiotic-response elements to regulate target genes, including xenobiotic-metabolising enzymes such as CYP1A1. AHR signalling also contributes to broader developmental, metabolic and immune regulatory programmes.
