Primärantikörper geliefert von Boster Bio
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Dieses Gen kodiert für das mitochondriale Enzym, das den geschwindigkeitsbestimmenden Schritt in der Häm-(Eisen-Protoporphyrin)-Biosynthese katalysiert. Das durch dieses Gen kodierte Enzym ist das Haushaltsenzym; ein separates Gen kodiert eine Form des Enzyms, die spezifisch für Erythroidgewebe ist. Der Spiegel des reifen kodierten Proteins wird durch Häm reguliert: Hohe Häm-Spiegel regulieren das reife Enzym in den Mitochondrien herunter, während niedrige Häm-Spiegel es hochregulieren. Ein Pseudogen dieses Gens befindet sich auf Chromosom 12. Alternatives Spleißen führt zu mehreren Transkriptvarianten, die verschiedene Isoformen kodieren.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Arten | WB | IHC | IHC-P | IHC-F | IF/ICC | Durchflusszytometrie | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.