Human Afamin, AFM ELISA Kit
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Functions as carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed: 26902720). Binds vitamin E (PubMed: 15952736, PubMed: 12463752). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed: 15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed: 19046407).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Cell culture supernatants | Ascites | Tissue homogenates |
|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Afamin (AFM) is a secreted albumin-family glycoprotein produced mainly by the liver. It is studied as a carrier of hydrophobic ligands, including vitamin E, and as an extracellular factor that can stabilize lipidated Wnt proteins.
Biological function: Human afamin is a secreted plasma and extravascular-fluid protein in the albumin family. Reviewed UniProt evidence supports binding of vitamin E and a probable carrier role for hydrophobic molecules. Afamin also forms complexes with lipidated Wnt family proteins and can support their solubility and extracellular activity.
