AGR2 Monoclonal Antibody
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N/A
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | WB | IHC-p | FCM | ELISA | IHC |
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This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AGR2 (anterior gradient 2, protein disulphide isomerase family member; PDIA17) is an endoplasmic-reticulum protein of the protein-disulfide-isomerase family. It is studied in protein folding, epithelial secretory biology, mucin production and ER proteostasis.
Biological function: AGR2 is an ER-localized protein-disulfide-isomerase-family molecular chaperone with a thioredoxin-like catalytic domain. NCBI describes roles in protein folding and thiol-disulfide interchange, while reviewed UniProt supports a requirement for MUC2 synthesis and secretion and a role in intestinal mucus production.
