Manufactured by:BT LAB
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CCR10 Monoclonal Antibody

CCR10 Monoclonal Antibody

SKU:
ABM202571
Manufacturer SKU
BT-MCA2860
Product type
Primary Antibodies
TargetCCR10
ApplicationsWB, IHC-P, IF/ICC, Flow Cytometry, ELISA, IHC

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Key facts & specifications
Research areas
Immunology
Also known as
GPR2
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Dilution range
WB: 1:500 - 1:2000; IHC-p: 1:200 - 1:1000; ICC: 1:200 - 1:1000; FCM: 1:200 - 1:400; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human CCR10 (AA: extra mix) expressed in E. Coli.
Molecular weight
38.4kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pICCFCMELISAIHC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA2860
Gene ID
2826
UniProt accession
P46092
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Purified antibody in PBS with 0.05% sodium azide
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

BT LAB
£240.93£205.00