Manufactured by:BT LAB
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GRIA2 Monoclonal Antibody

GRIA2 Monoclonal Antibody

SKU:
ABM201461
Manufacturer SKU
BT-MCA2305
Product type
Primary Antibodies
TargetGRIA2
ApplicationsWB, Flow Cytometry, ELISA
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Key facts & specifications
Research areas
Neuroscience
Also known as
GluA2;GluR2;gluR-B;GluR-K2
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Dilution range
WB: 1:500 - 1:2000; FCM: 1:200 - 1:400; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.
Molecular weight
98.8kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBFCMELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA2305
Gene ID
2891
UniProt accession
P42262
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Purified antibody in PBS with 0.05% sodium azide
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GRIA2glutamate ionotropic receptor AMPA type subunit 2

View target guide

GRIA2 identifies glutamate ionotropic receptor AMPA type subunit 2 in Homo sapiens (Human). This target record connects NCBI Gene 2891, UniProtKB P42262 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
2891
UniProtKB
P42262
BT LAB
£240.93£205.00