Manufactured by:BT LAB
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MMP-9 Monoclonal Antibody

MMP-9 Monoclonal Antibody

SKU:
ABM200091
Manufacturer SKU
BT-MCA0890
Product type
Primary Antibodies
TargetMMP9
ApplicationsFlow Cytometry, IF/ICC, IHC, WB, IHC-P, ELISA
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Key facts & specifications
Research areas
Signal Transduction, Cancer, Cell Biology, Cardiovascular
Also known as
MMP9; CLG4B; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
FC: 1:200 - 1:400; IF: 1:200 - 1:1000; IHC: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human MMP-9 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceFCIFIHCWBIHC-pICCFCMELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0890
Gene ID
4318
UniProt accession
P14780
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MMP9matrix metallopeptidase 9

View target guide

MMP9 identifies matrix metallopeptidase 9 in Homo sapiens (Human). This target record connects NCBI Gene 4318, UniProtKB P14780 and related ABMIUM catalogue products.

Biological function: MMP9 is a matrix metalloproteinase that contributes to local extracellular-matrix proteolysis and leukocyte migration. It can cleave extracellular-matrix substrates including type IV and type V collagens.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4318
UniProtKB
P14780
BT LAB
£135.52£115.00