Manufactured by:BT LAB
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Mcl-1 Monoclonal Antibody

Mcl-1 Monoclonal Antibody

SKU:
ABM200050
Manufacturer SKU
BT-MCA0871
Product type
Primary Antibodies
TargetMCL1
ApplicationsELISA, IF/ICC, IHC, WB, IHC-P
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Key facts & specifications
Research areas
Cancer, Cell Biology, Metabolism
Also known as
MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT; mcl1; mcl1; EAT
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; IF: 1:200 - 1:1000; IHC: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human MCL-1 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAIFIHCWBIHC-pICC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0871
Gene ID
4170
UniProt accession
Q07820
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Purified antibody in PBS containing 0.03% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MCL1MCL1 apoptosis regulator, BCL2 family member

View target guide

MCL1 identifies MCL1 apoptosis regulator, BCL2 family member in Homo sapiens (Human). This target record connects NCBI Gene 4170, UniProtKB Q07820 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4170
UniProtKB
Q07820
BT LAB
£135.52£115.00