Manufactured by:BT LAB
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FGF-2 Monoclonal Antibody

FGF-2 Monoclonal Antibody

SKU:
ABM199530
Manufacturer SKU
BT-MCA0533
Product type
Primary Antibodies
TargetFGF2
ApplicationsELISA, IHC, WB, IHC-P, IF/ICC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Key facts & specifications
Research areas
Signal Transduction, Cancer, Cardiovascular, Stem Cells, Neuroscience, Developmental Biology
Also known as
FGF2; FGFB; Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; IHC: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of FGF-2 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAIHCWBIHC-pIF
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0533
Gene ID
2247
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

FGF2fibroblast growth factor 2

View target guide

FGF2 identifies fibroblast growth factor 2 in Homo sapiens (Human). This target record connects NCBI Gene 2247, UniProtKB P09038 and related ABMIUM catalogue products.

Biological function: FGF2 is a fibroblast growth factor that signals through FGFR1-4 and regulates cell survival, division, differentiation and migration. It is a potent mitogen and can promote angiogenesis.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
2247
UniProtKB
P09038
BT LAB
£135.52£115.00