Manufactured by:BT LAB
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Crk-L Monoclonal Antibody

Crk-L Monoclonal Antibody

SKU:
ABM199261
Manufacturer SKU
BT-MCA0388
Product type
Primary Antibodies
TargetCRKL
ApplicationsELISA, Flow Cytometry, WB
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction, Cancer
Also known as
CRKL; Crk-like protein
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; FC: 1:200 - 1:400; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human Crk-L expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAFCWBFCM
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0388
Gene ID
1399
UniProt accession
P46109
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CRKLCRK like proto-oncogene, adaptor protein

View target guide

CRKL identifies CRK like proto-oncogene, adaptor protein in Homo sapiens (Human). This target record connects NCBI Gene 1399, UniProtKB P46109 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
1399
UniProtKB
P46109
BT LAB
£135.52£115.00