Manufactured by:BT LAB
Save 15%RUO

CD276 Monoclonal Antibody

CD276 Monoclonal Antibody

SKU:
ABM199125
Manufacturer SKU
BT-MCA0293
Product type
Primary Antibodies
TargetCD276
ApplicationsELISA, Flow Cytometry, IHC, WB, IHC-P, IF/ICC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Key facts & specifications
Research areas
Immunology, Cancer, Stem Cells
Also known as
CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD antigen CD276
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; FC: 1:200 - 1:400; IHC: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human CD276 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAFCIHCWBIHC-pIFFCM
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0293
Gene ID
80381
UniProt accession
Q5ZPR3
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CD276CD276 molecule

View target guide

CD276 identifies CD276 molecule in Homo sapiens (Human). This target record connects NCBI Gene 80381, UniProtKB Q5ZPR3 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
80381
UniProtKB
Q5ZPR3
BT LAB
£135.52£115.00